All About Nursing · Hospice & Palliative Care

Pain Management: Addiction, Dependence, Pseudoaddiction, and Tolerance

Addiction: Compulsive use of a substance that occurs when it is used in a way other than intended. Patients have cravings when the substance is withdrawn, with an overriding inability to control their perceived need for the substance, even though there may be an awareness that the substance, or overuse of the substance, is harmful.

Dependence: A state in which the person feels that they can only function normally when using a specific substance. Abrupt withdrawal of the substance causes withdrawal symptoms.

Pseudoaddiction: The mistaken assumption that a patient who is seeking pain relief is addicted to a substance.

Tolerance: Occurs when the patient no longer has a therapeutic response to the drug and a higher dose is required to achieve the prior effectiveness.

Mental Disorders · Nursing Continue Education

Alcohol-Related Disorders / Self Review & Study


  • brain depressant
  • a cause of considerable morbidity and mortality

Dopamine is one of the primary neurotransmitters within the CNS and is known to be involved in the integration of environmental stimuli with physiologic responses. Cannabis, cocaine, and alcohol increase the dopamine level, thereby producing a strong association between physiologic effects and behavior.

Diagnostic Evaluation ( measurement tools for alcohol abuse or dependence ):

  • CAGE
  • Michigan Alcohol Screening Test (MAST)
  • The Alcohol Use Disorders Identification Test (AUDIT)


Alcohol-related disorders:

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