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Mechanical Ventilation (Reading & Sharing)

The clinical applications of ventilation and the use of specific modes during the acute stage of illness focus on protecting the lung and improving the patient outcomes.

Acute respiratory distress syndrome (ARDS), the most severe presentation of acute lung injury, results from an acute insult to the body that may be direct or indirect (pneumonia vs sepsis). The release of mediators and a host of other toxic substances affect the alveolar- capillary permeability adversely and result in a noncardiac pulmonary edema. Pathology includes decreased compliance, shunting, and refractory hypoxemia. No definitive treatment, but the therapy focus on managing the underlying condition and on supportive mechanical ventilation.

The two most common types of ventilations:

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All About Nursing · CNE self study · Hospice & Palliative Care · Nursing Continue Education

Death Rattle and Anticholinergic Medications

Death rattle – as patients near death, they are unable to cough to clear secretions that begin to pool in the oropharynx and bronchi, resulting in rales (“death rattles”). Because the sound is often distressing to family members, an anticholinergic (glycopyrrolate or atropine) may be given subcutaneously to relieve respiratory distress. A hyoscine hydrobromide transdermal patch is also available, but action is slower, 12 hours compared to 1 minute for injections. Risks associated with anticholinergics include xerostomia (dry mouth), increased sedation, and increased delirium. Elevating the head of the bed or turning the patient to the side may also relieve rattling. Patients normally stop taking fluids as they near death, resulting in dehydration and drying of the mucous membranes of the mouth. The death rattle also begins to lessen.

Palliative care is a form of specialized medical care which aims to optimize the quality of life and alleviate the suffering of patients through early identification and treatment of new symptoms along with management of those that prove refractory.

Excessive secretions can cause the frequently noted ” death rattle” in patients that are actively dying. This is caused by relaxation of the oropharyngeal muscles leading to a pooling of secretion in the throat. While it is typically not distressing for the patient, it does often make family members and other visitors uncomfortable. Anticholinergic agents, especially sublingual atropine drops, can be administered to assist in secretion reduction. Anticholinergic agents have multiple side effects, including decreased/ absent bowel sounds, decreased sweating, hot skin, and mydriatic pupils (dilated pupils).

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Anxiety, Depression, Caregiver Burnout, Grief, Anger, Frustration in End of Life Care

Anxiety

  • According to the DSM-5, anxiety disorders are those that share features of excessive anxiety and fear with related behavioral disturbances.
  • These disorders differ from normal fear and anxiety in their being excessive and persisting beyond developmentally appropriate periods, typically lasting 6 months or more
  • Types of anxiety:
    1. Separation anxiety – anxiety or fear about separation from an attachment figure
    2. Selective mutism- consistent failure to speak in social situations
    3. Social anxiety – fear or anxiety about social interactions or situations
    4. Panic disorder -recurrent panic attacks
    5. Phobias- fear of a specific object or situation
    6. Generalized anxiety disorder- persistent or excessive anxiety and worry about various domains.
  • Treatment:
    • Nonpharmacological interventions
      1. Establish a trusting relationship
      2. Be aware of any anxiety that you as a nurse may have that may be picked up on
      3. Do not leave a person experiencing an anxiety disorder exacerbation alone
      4. Maintain a calm, nonthreatening, manner-of-fact approach
      5. Keep stimuli minimized
      6. Use simple words and brief messages that are calmly and clearly explained
      7. Discuss the reality of the situation
      8. Include person on decision-making to feel more in control
      9. Encourage exploration of underlying feelings that contribute to irrational fears
      10. Teach and reinforce stress management /relaxation techniques
    • Pharmacological interventions
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Dysphagia

Dysphagia is characterized by difficulty swallowing solids and /or liquids and may arise from a variety of underlying conditions, including cognitive impairment, weakness, mechanical obstruction, and incoordination. Presenting symptoms may include prolonged meal times, avoidance of certain foods/liquids, new head or body movements during meals, voice changes with eating, coughing, choking, or unexplained weight loss. Dysphagia place the patient at increased risk for aspiration and malnutrition.

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Hypercalcemia at the End of Life

  • Hypercalcemia is associated with several cancers, most commonly breast, lung, lymphoma, and multiple myeloma. Hypercalcemia in the setting of advanced cancer may be caused by release of calcium due to bone metastases, solid tumor release of PTHrP (parathyroid hormone-related protein), or tumor production of calcitriol leading to increased intestinal calcium resorption. Hypercalcemia in cancer patients is indicative of widespread disease and is associated with a poor prognosis for long-term survival.
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